Rapid, Low Cost, Animal-Free VHH (Nanobody™) Discovery Service

Powered by our proprietary synthetic phage-display library, QBI’s AbSynth™ VHH Service can take you from target to binders in 4-6 weeks for about $10,000 per target.

A superior alternative to rodent, rabbit, and chicken derived monoclonal and polyclonal antibodies - use our VHHs as high-affinity, high-specificity capture/detection reagents in sandwich ELISAs, western blots, flow cytometry, and immunohistochemistry. Minimize steric hindrance all while ensuring efficient epitope recognition!

Once antigen is provided, library panning is performed to select for binders to a target of interest.

ELISAs demonstrate that we have found isolated binders that perform comparably to reference antibody standards.

What Makes Our Approach Superior?

  • Rapid turnaround: Receive sequences in 4-6 weeks from a US-based laboratory

  • Animal-free: No alpacas/llamas or inoculation necessary

  • Cost-effective: Starting at $10,000 per target

  • Compact: Access hidden/recessed targets with VHHs (compared to full-length Abs)

  • Options: Custom tags and other modifications (e.g., fluorophores) available

  • Service: Our dedicated, San Diego-based team will deliver regular updates, detailed reports, and answer your questions

Our fully synthetic library offers more diversity than a naive animal library, and our AI-enabled approach can rapidly select customized binders.

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